What is esomeprazole magnesium trihydrate?

Esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

What ingredients are in Nexium?

Each delayed-release capsule contains 20 mg or 40 mg of esomeprazole (present as 22.3 mg or 44.5 mg esomeprazole magnesium trihydrate) in the form of enteric-coated granules with the following inactive ingredients: glyceryl monostearate 40-55, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid …

Is esomeprazole hazardous?

Esomeprazole gastro-resistant tablets CAS No. : Not applicable. Hazard statements : H317 May cause an allergic skin reaction. H412 Harmful to aquatic life with long lasting effects.

What is the difference between esomeprazole and esomeprazole magnesium?

Esomeprazole sodium is available in an intravenous (IV) form, which is only given by a healthcare provider. Esomeprazole magnesium oral capsule is used to treat conditions caused by too much acid production in your stomach.

Is esomeprazole the same as Nexium?

Nexium, also known by its generic name esomeprazole, is one of the most widely prescribed drugs for stomach-acid-related conditions in the United States. Americans may know the drug by its nickname, “The Purple Pill.” Nexium comes in several versions. It premiered as a prescription drug in 1989.

Is esomeprazole magnesium the same as Nexium?

Esomeprazole magnesium is available as the brand-name drug Nexium and as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. Esomeprazole magnesium may be used as part of a combination therapy.

Does Nexium contain polyethylene glycol?

Non-medicinal ingredients: NEXIUM tablet (delayed release): cellulose microcrystalline, crospovidone, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, iron oxide, magnesium stearate, methacrylic acid ethylacrylate copolymer, polyethylene glycol, polysorbate, synthetic paraffin, sodium stearyl fumarate.

Which is stronger omeprazole or esomeprazole?

In conclusion, esomeprazole 40 mg provides more effective acid control than twice the standard dose of omeprazole.

What is the difference between omeprazole and esomeprazole in chemical structure?

Omeprazole is a mixture of two stereo-isomers: R-omeprazole and S-omeprazole. Stereo-isomers are compounds that have the same chemical formula but differ only in their arrangement of atoms. Esomeprazole contains only one isomer, S- omeprazole.

What is the chemical name of esomeprazole?

Esomeprazole magnesium

Can you drink alcohol with esomeprazole?

Alcohol does not affect the way esomeprazole works, but it makes your stomach produce more acid than normal. This can irritate your stomach lining and make your symptoms worse.

Is esomeprazole magnesium safe?

Esomeprazole magnesium can increase the levels of methotrexate in your body. This may cause dangerous side effects. These side effects can include nausea, vomiting, headache, fatigue, and liver and kidney damage.

What drugs contain polyethylene glycol?

Top medications with this excipient

• Acetaminophen 500mg.
• Acetaminophen Extended Release 650 mg.
• Cetirizine Hydrochloride 10 mg.
• Cyclobenzaprine Hydrochloride 10 mg.
• Cyclobenzaprine Hydrochloride 10 mg.
• Cyclobenzaprine Hydrochloride 10 mg.
• Cyclobenzaprine Hydrochloride 10 mg.
• Cyclobenzaprine Hydrochloride 10 mg.

Which products contain polyethylene glycol?

Polyethylene glycol (PEG) is found in many skin creams, lotions, soaps, hair products and shower gels. PEGs are petroleum-based compound that are often used as thickeners, solvents, softeners, and moisture-carriers.

Why is esomeprazole the best PPI?

Esomeprazole is the latest PPI and was developed as the S-isomer of omeprazole as an attempt to improve its pharmacokinetic properties. Esomeprazole has been reported to have a somewhat higher potency in acid inhibition than other PPIs.

Why is esomeprazole more potent than omeprazole?

This means that there are higher levels of the drug in your bloodstream, and esomeprazole may decrease acid production for a longer period of time. It may also work slightly faster to treat your symptoms compared with omeprazole.

Does esomeprazole affect blood pressure?

Esomeprazole magnesium can increase the levels of tacrolimus in your body. This may cause high blood pressure and kidney damage.

Is it OK to take antacid after drinking alcohol?

It’s safe to drink alcohol if you take Tums. There’s no known interaction between calcium carbonate and alcohol. With that said, keep in mind that alcohol can aggravate heartburn and other symptoms associated with indigestion. The reason for this is because alcoholic beverages can increase gastric acid secretions.

Can I drink alcohol while taking PPI?

Drinking alcohol while taking PPIs can result in increased side effects and the worsening of gastrointestinal problems. It’s also possible alcohol will worsen the conditions PPIs are intended to treat, such as heartburn caused by acid reflux (GERD) and stomach ulcers.

Can esomeprazole cause kidney damage?

Patients taking PPIs 28.4 times more likely to develop chronic kidney disease. People taking protein pump inhibitors (PPIs) such as omeprazole (Prilosec), esomeprazole (Nexium) and lansoprazole (Prevacid) have a higher risk of developing kidney disease, a new study says.

Is polyethylene glycol an alcohol?

Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water.

Is glycol an alcohol?

Glycols are alcohols with two OH groups on adjacent carbon atoms. Glycerol is the most important trihydroxy alcohol.

What is the formula for esomeprazole magnesium trihydrate?

CID 130565 PubChem CID 130565 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C34H42MgN6O9S2 Synonyms Esomeprazole magnesium trihydrate 217087

What is the product code for esomeprazole?

Trade name : ESOMEPRAZOLE MAGNESIUM TRIHYDRATE CRS CAS No : 217087-09-7 Product code : Y0001028 Other means of identification : RTECS No : DD9087300 (esomeprazole)

What is the difference between esomeprazole and magnesium?

More… Esomeprazole Magnesium is the magnesium salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity.

What is the LD50 level of esomeprazole?

ESOMEPRAZOLE MAGNESIUM TRIHYDRATE CRS(217087-09-7) LD50 oral rat 1900 mg/kg ATE (oral) 500,000 mg/kg Skin corrosion/irritation : Not classified